Gene basic information
| LiverAtlas Gene ID |
HuLG001205 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DHODH |
|
Synonyms |
DHOdehase|POADS|URA1 |
|
Gene name |
dihydroorotate dehydrogenase |
|
Gene Type |
protein-coding |
|
Chromosome |
16 |
|
Genomics Location |
16q22 |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2867
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004152 |
dihydroorotate dehydrogenase activity |
|
GO:0004158 |
dihydroorotate oxidase activity |
|
GO:0005739 |
mitochondrion |
|
GO:0005743 |
mitochondrial inner membrane |
|
GO:0006206 |
pyrimidine base metabolic process |
|
GO:0006207 |
de novo' pyrimidine base biosynthetic process |
|
GO:0006221 |
pyrimidine nucleotide biosynthetic process |
|
GO:0006222 |
UMP biosynthetic process |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0046134 |
pyrimidine nucleoside biosynthetic process |
|
GO:0055086 |
nucleobase, nucleoside and nucleotide metabolic process |
|
GO:0090140 |
regulation of mitochondrial fission |
