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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001208

Entrez Gene ID

1728

Official Gene Symbol

NQO1

Synonyms

DHQU|DIA4|DTD|NMOR1|NMORI|QR1

Gene name

NAD(P)H dehydrogenase, quinone 1

Gene Type

protein-coding

Chromosome

16

Genomics Location

16q22.1

Known cancer genes

Yes

Protein products

NAD(P)H dehydrogenase, quinone 1, isoform CRA b

NAD(P)H dehydrogenase [quinone] 1

Related liver disease name

Hepatitis

Drug-induced hepatitis

Hepatocellular carcinoma

Database cross reference

HGNC:2874
MIM:125860
Ensembl:ENSG00000181019
HPRD:00518
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003955

NAD(P)H dehydrogenase (quinone) activity

GO:0004128

cytochrome-b5 reductase activity

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006521

regulation of cellular amino acid metabolic process

GO:0006805

xenobiotic metabolic process

GO:0006809

nitric oxide biosynthetic process

GO:0006979

response to oxidative stress

GO:0007271

synaptic transmission, cholinergic

GO:0009055

electron carrier activity

GO:0009636

response to toxin

GO:0016491

oxidoreductase activity

GO:0034641

cellular nitrogen compound metabolic process

GO:0043525

positive regulation of neuron apoptosis

GO:0050662

coenzyme binding