HuLG001213

Entrez Gene ID

1734

Official Gene Symbol

DIO2

Synonyms

5DII|D2|DIOII|SelY|TXDI2

Gene name

deiodinase, iodothyronine, type II

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q24.2-q24.3

Known cancer genes

Yes

Protein products

Type II iodothyronine deiodinase

DIO2 protein

Type II iodothyronine deiodinase

Database cross reference

HGNC:2884
MIM:601413
Ensembl:ENSG00000211448
HPRD:09027
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192

GO annotation

GO:0001514

selenocysteine incorporation

GO:0004800

thyroxine 5'-deiodinase activity

GO:0005886

plasma membrane

GO:0006590

thyroid hormone generation

GO:0008430

selenium binding

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0031625

ubiquitin protein ligase binding

GO:0034641

cellular nitrogen compound metabolic process

GO:0042403

thyroid hormone metabolic process

GO:0042446

hormone biosynthetic process