HuLG001216

Entrez Gene ID

1737

Official Gene Symbol

DLAT

Synonyms

DLTA|PDCNE2|PDCE2

Gene name

dihydrolipoamide S-acetyltransferase

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q23.1

Protein products

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

Dihydrolipoamide S-acetyltransferase

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis C

Chronic hepatitis C

Autoimmune hepatitis

Primary biliary cirrhosis

Database cross reference

HGNC:2896
MIM:608770
Ensembl:ENSG00000150768
HPRD:10578
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

GO annotation

GO:0004742

dihydrolipoyllysine-residue acetyltransferase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0005967

mitochondrial pyruvate dehydrogenase complex

GO:0006085

acetyl-CoA biosynthetic process

GO:0006090

pyruvate metabolic process

GO:0006096

glycolysis

GO:0008152

metabolic process

GO:0008415

acyltransferase activity

GO:0010510

regulation of acetyl-CoA biosynthetic process from pyruvate

GO:0016740

transferase activity

GO:0030431

sleep