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Gene basic information

LiverAtlas Gene ID

HuLG001224

Entrez Gene ID

1746

Official Gene Symbol

DLX2

Synonyms

TESN1|TES1

Gene name

distal-less homeobox 2

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q32

Known cancer genes

Yes

Protein products

Homeobox protein DLX-2

Distal-less homeobox 2

Database cross reference

HGNC:2915
MIM:126255
Ensembl:ENSG00000115844
HPRD:00527
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003682

chromatin binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003727

single-stranded RNA binding

GO:0005634

nucleus

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0007275

multicellular organismal development

GO:0007420

brain development

GO:0009954

proximal/distal pattern formation

GO:0021766

hippocampus development

GO:0021772

olfactory bulb development

GO:0021879

forebrain neuron differentiation

GO:0021882

regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment

GO:0021893

cerebral cortex GABAergic interneuron fate commitment

GO:0030154

cell differentiation

GO:0042475

odontogenesis of dentine-containing tooth

GO:0043565

sequence-specific DNA binding

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048701

embryonic cranial skeleton morphogenesis

GO:0048706

embryonic skeletal system development

GO:0048715

negative regulation of oligodendrocyte differentiation

GO:0048755

branching morphogenesis of a nerve

GO:0051216

cartilage development