Gene basic information
| LiverAtlas Gene ID |
HuLG001250 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DNMT1 |
|
Synonyms |
AIM|CXXC9|DNMT|FLJ16293|MCMT|MGC104992 |
|
Gene name |
DNA (cytosine-5-)-methyltransferase 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
19 |
|
Genomics Location |
19p13.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2976
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0003677 |
DNA binding |
|
GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005657 |
replication fork |
|
GO:0005721 |
centromeric heterochromatin |
|
GO:0006306 |
DNA methylation |
|
GO:0008134 |
transcription factor binding |
|
GO:0008270 |
zinc ion binding |
|
GO:0009008 |
DNA-methyltransferase activity |
|
GO:0010216 |
maintenance of DNA methylation |
|
GO:0010628 |
positive regulation of gene expression |
|
GO:0016458 |
gene silencing |
|
GO:0016568 |
chromatin modification |
|
GO:0016740 |
transferase activity |
|
GO:0042127 |
regulation of cell proliferation |
|
GO:0046872 |
metal ion binding |
|
GO:0051571 |
positive regulation of histone H3-K4 methylation |
|
GO:0051573 |
negative regulation of histone H3-K9 methylation |
|
GO:0090116 |
C-5 methylation of cytosine |
