Gene basic information
LiverAtlas Gene ID |
HuLG001252 |
Entrez Gene ID |
|
Official Gene Symbol |
DNMT3A |
Synonyms |
DNMT3A2|M.HsaIIIA |
Gene name |
DNA (cytosine-5-)-methyltransferase 3 alpha |
Gene Type |
protein-coding |
Chromosome |
2 |
Genomics Location |
2p23 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:2978
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
GO:0000775 |
chromosome, centromeric region |
GO:0000791 |
euchromatin |
GO:0003677 |
DNA binding |
GO:0003682 |
chromatin binding |
GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005720 |
nuclear heterochromatin |
GO:0005737 |
cytoplasm |
GO:0006306 |
DNA methylation |
GO:0006346 |
methylation-dependent chromatin silencing |
GO:0006349 |
regulation of gene expression by genetic imprinting |
GO:0007283 |
spermatogenesis |
GO:0008168 |
methyltransferase activity |
GO:0016363 |
nuclear matrix |
GO:0016568 |
chromatin modification |
GO:0016740 |
transferase activity |
GO:0043045 |
DNA methylation involved in embryo development |
GO:0043046 |
DNA methylation involved in gamete generation |
GO:0046872 |
metal ion binding |
GO:0090116 |
C-5 methylation of cytosine |