Gene basic information
| LiverAtlas Gene ID |
HuLG001253 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DNMT3B |
|
Synonyms |
ICF|M.HsaIIIB |
|
Gene name |
DNA (cytosine-5-)-methyltransferase 3 beta |
|
Gene Type |
protein-coding |
|
Chromosome |
20 |
|
Genomics Location |
20q11.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:2979
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0003677 |
DNA binding |
|
GO:0003714 |
transcription corepressor activity |
|
GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005720 |
nuclear heterochromatin |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0006306 |
DNA methylation |
|
GO:0006346 |
methylation-dependent chromatin silencing |
|
GO:0006349 |
regulation of gene expression by genetic imprinting |
|
GO:0009008 |
DNA-methyltransferase activity |
|
GO:0010212 |
response to ionizing radiation |
|
GO:0010424 |
DNA methylation on cytosine within a CG sequence |
|
GO:0010628 |
positive regulation of gene expression |
|
GO:0016740 |
transferase activity |
|
GO:0031503 |
protein complex localization |
|
GO:0042493 |
response to drug |
|
GO:0043231 |
intracellular membrane-bounded organelle |
|
GO:0045322 |
unmethylated CpG binding |
|
GO:0045666 |
positive regulation of neuron differentiation |
|
GO:0046498 |
S-adenosylhomocysteine metabolic process |
|
GO:0046499 |
S-adenosylmethioninamine metabolic process |
|
GO:0046872 |
metal ion binding |
|
GO:0051571 |
positive regulation of histone H3-K4 methylation |
|
GO:0051573 |
negative regulation of histone H3-K9 methylation |
|
GO:0051718 |
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates |
|
GO:0090116 |
C-5 methylation of cytosine |
