Gene basic information
| LiverAtlas Gene ID |
HuLG001274 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DRD2 |
|
Synonyms |
D2DR|D2R |
|
Gene name |
dopamine receptor D2 |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11q23 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3023
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001591 |
dopamine receptor activity, coupled via Gi/Go |
|
GO:0001659 |
temperature homeostasis |
|
GO:0001666 |
response to hypoxia |
|
GO:0001669 |
acrosomal vesicle |
|
GO:0001670 |
dopamine D2 receptor activity |
|
GO:0001963 |
synaptic transmission, dopaminergic |
|
GO:0001975 |
response to amphetamine |
|
GO:0001976 |
neurological system process involved in regulation of systemic arterial blood pressure |
|
GO:0002027 |
regulation of heart rate |
|
GO:0002028 |
regulation of sodium ion transport |
|
GO:0002031 |
G-protein coupled receptor internalization |
|
GO:0002052 |
positive regulation of neuroblast proliferation |
|
GO:0002092 |
positive regulation of receptor internalization |
|
GO:0004872 |
receptor activity |
|
GO:0004930 |
G-protein coupled receptor activity |
|
GO:0005102 |
receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005625 |
soluble fraction |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006874 |
cellular calcium ion homeostasis |
|
GO:0007188 |
G-protein signaling, coupled to cAMP nucleotide second messenger |
|
GO:0007194 |
negative regulation of adenylate cyclase activity |
|
GO:0007195 |
inhibition of adenylate cyclase activity by dopamine receptor signaling pathway |
|
GO:0007243 |
intracellular protein kinase cascade |
|
GO:0007270 |
neuron-neuron synaptic transmission |
|
GO:0007409 |
axonogenesis |
|
GO:0007416 |
synapse assembly |
|
GO:0007608 |
sensory perception of smell |
|
GO:0007616 |
long-term memory |
|
GO:0007625 |
grooming behavior |
|
GO:0007626 |
locomotory behavior |
|
GO:0007628 |
adult walking behavior |
|
GO:0007631 |
feeding behavior |
|
GO:0008104 |
protein localization |
|
GO:0008144 |
drug binding |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0008306 |
associative learning |
|
GO:0008542 |
visual learning |
|
GO:0009416 |
response to light stimulus |
|
GO:0009636 |
response to toxin |
|
GO:0010039 |
response to iron ion |
|
GO:0014059 |
regulation of dopamine secretion |
|
GO:0014069 |
postsynaptic density |
|
GO:0015459 |
potassium channel regulator activity |
|
GO:0016055 |
Wnt receptor signaling pathway |
|
GO:0016328 |
lateral plasma membrane |
|
GO:0019861 |
flagellum |
|
GO:0021853 |
cerebral cortex GABAergic interneuron migration |
|
GO:0021984 |
adenohypophysis development |
|
GO:0030139 |
endocytic vesicle |
|
GO:0030336 |
negative regulation of cell migration |
|
GO:0030424 |
axon |
|
GO:0030425 |
dendrite |
|
GO:0030432 |
peristalsis |
|
GO:0030672 |
synaptic vesicle membrane |
|
GO:0030814 |
regulation of cAMP metabolic process |
|
GO:0030900 |
forebrain development |
|
GO:0031223 |
auditory behavior |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0032147 |
activation of protein kinase activity |
|
GO:0032228 |
regulation of synaptic transmission, GABAergic |
|
GO:0032922 |
circadian regulation of gene expression |
|
GO:0034776 |
response to histamine |
|
GO:0035094 |
response to nicotine |
|
GO:0035255 |
ionotropic glutamate receptor binding |
|
GO:0040018 |
positive regulation of multicellular organism growth |
|
GO:0042220 |
response to cocaine |
|
GO:0042321 |
negative regulation of circadian sleep/wake cycle, sleep |
|
GO:0042417 |
dopamine metabolic process |
|
GO:0042493 |
response to drug |
|
GO:0043197 |
dendritic spine |
|
GO:0043204 |
perikaryon |
|
GO:0043266 |
regulation of potassium ion transport |
|
GO:0043278 |
response to morphine |
|
GO:0043408 |
regulation of MAPKKK cascade |
|
GO:0043473 |
pigmentation |
|
GO:0043666 |
regulation of phosphoprotein phosphatase activity |
|
GO:0043679 |
axon terminus |
|
GO:0045745 |
positive regulation of G-protein coupled receptor protein signaling pathway |
|
GO:0045776 |
negative regulation of blood pressure |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046488 |
phosphatidylinositol metabolic process |
|
GO:0046676 |
negative regulation of insulin secretion |
|
GO:0048148 |
behavioral response to cocaine |
|
GO:0048149 |
behavioral response to ethanol |
|
GO:0048169 |
regulation of long-term neuronal synaptic plasticity |
|
GO:0048678 |
response to axon injury |
|
GO:0048755 |
branching morphogenesis of a nerve |
|
GO:0050482 |
arachidonic acid secretion |
|
GO:0050709 |
negative regulation of protein secretion |
|
GO:0051209 |
release of sequestered calcium ion into cytosol |
|
GO:0051481 |
reduction of cytosolic calcium ion concentration |
|
GO:0051482 |
elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger |
|
GO:0051584 |
regulation of dopamine uptake |
|
GO:0051586 |
positive regulation of dopamine uptake |
|
GO:0051898 |
negative regulation of protein kinase B signaling cascade |
|
GO:0051927 |
negative regulation of calcium ion transport via voltage-gated calcium channel activity |
|
GO:0051967 |
negative regulation of synaptic transmission, glutamatergic |
|
GO:0060124 |
positive regulation of growth hormone secretion |
|
GO:0060134 |
prepulse inhibition |
|
GO:0060158 |
activation of phospholipase C activity by dopamine receptor signaling pathway |
|
GO:0060160 |
negative regulation of dopamine receptor signaling pathway |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
