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Gene basic information

LiverAtlas Gene ID

HuLG001301

Entrez Gene ID

1845

Official Gene Symbol

DUSP3

Synonyms

VHR

Gene name

dual specificity phosphatase 3

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q21

Known cancer genes

Yes

Protein products

Dual specificity phosphatase 3

Dual specificity protein phosphatase 3

Database cross reference

HGNC:3069
MIM:600183
Ensembl:ENSG00000108861
HPRD:02553
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

 

Ontology annotation

GO ID

GO annotation

GO:0000188

inactivation of MAPK activity

GO:0001701

in utero embryonic development

GO:0001772

immunological synapse

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0004725

protein tyrosine phosphatase activity

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005829

cytosol

GO:0008063

Toll signaling pathway

GO:0008138

protein tyrosine/serine/threonine phosphatase activity

GO:0016787

hydrolase activity

GO:0033549

MAP kinase phosphatase activity

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0035335

peptidyl-tyrosine dephosphorylation

GO:0043409

negative regulation of MAPKKK cascade

GO:0045087

innate immune response

GO:0045931

positive regulation of mitotic cell cycle

GO:0046329

negative regulation of JNK cascade

GO:0048011

nerve growth factor receptor signaling pathway

GO:0050860

negative regulation of T cell receptor signaling pathway

GO:0050868

negative regulation of T cell activation

GO:0051403

stress-activated MAPK cascade

GO:0070373

negative regulation of ERK1 and ERK2 cascade