Gene basic information
| LiverAtlas Gene ID |
HuLG001310 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
DVL2 |
|
Gene name |
dishevelled, dsh homolog 2 (Drosophila) |
|
Gene Type |
protein-coding |
|
Chromosome |
17 |
|
Genomics Location |
17p13.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3086
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001843 |
neural tube closure |
|
GO:0001934 |
positive regulation of protein phosphorylation |
|
GO:0003007 |
heart morphogenesis |
|
GO:0004871 |
signal transducer activity |
|
GO:0005109 |
frizzled binding |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0006366 |
transcription from RNA polymerase II promoter |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007379 |
segment specification |
|
GO:0007507 |
heart development |
|
GO:0019904 |
protein domain specific binding |
|
GO:0022007 |
convergent extension involved in neural plate elongation |
|
GO:0030136 |
clathrin-coated vesicle |
|
GO:0034613 |
cellular protein localization |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0035567 |
non-canonical Wnt receptor signaling pathway |
|
GO:0042802 |
identical protein binding |
|
GO:0043507 |
positive regulation of JUN kinase activity |
|
GO:0044340 |
canonical Wnt receptor signaling pathway involved in regulation of cell proliferation |
|
GO:0045177 |
apical part of cell |
|
GO:0045893 |
positive regulation of transcription, DNA-dependent |
|
GO:0051091 |
positive regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0060070 |
canonical Wnt receptor signaling pathway |
|
GO:0060071 |
Wnt receptor signaling pathway, planar cell polarity pathway |
|
GO:0061098 |
positive regulation of protein tyrosine kinase activity |
|
GO:0090103 |
cochlea morphogenesis |
|
GO:0090179 |
planar cell polarity pathway involved in neural tube closure |
