Gene basic information
LiverAtlas Gene ID |
HuLG001330 |
Entrez Gene ID |
|
Official Gene Symbol |
S1PR1 |
Synonyms |
CHEDG1|D1S3362|ECGF1|EDGN1|EDG1|FLJ58121|S1P1 |
Gene name |
sphingosine-1-phosphate receptor 1 |
Gene Type |
protein-coding |
Chromosome |
1 |
Genomics Location |
1p21 |
Known cancer genes |
Yes |
Protein products |
|
Database cross reference |
HGNC:3165
|
Ontology annotation
GO ID |
GO annotation |
GO:0001525 |
angiogenesis |
GO:0001619 |
lysosphingolipid and lysophosphatidic acid receptor activity |
GO:0004872 |
receptor activity |
GO:0004930 |
G-protein coupled receptor activity |
GO:0005886 |
plasma membrane |
GO:0007155 |
cell adhesion |
GO:0007186 |
G-protein coupled receptor protein signaling pathway |
GO:0007193 |
inhibition of adenylate cyclase activity by G-protein signaling pathway |
GO:0007420 |
brain development |
GO:0009897 |
external side of plasma membrane |
GO:0016021 |
integral to membrane |
GO:0019226 |
transmission of nerve impulse |
GO:0030155 |
regulation of cell adhesion |
GO:0030182 |
neuron differentiation |
GO:0030335 |
positive regulation of cell migration |
GO:0032320 |
positive regulation of Ras GTPase activity |
GO:0045446 |
endothelial cell differentiation |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046625 |
sphingolipid binding |
GO:0048661 |
positive regulation of smooth muscle cell proliferation |
GO:0050927 |
positive regulation of positive chemotaxis |
GO:0051482 |
elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger |
GO:0051497 |
negative regulation of stress fiber assembly |