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Gene basic information

LiverAtlas Gene ID

HuLG001330

Entrez Gene ID

1901

Official Gene Symbol

S1PR1

Synonyms

CHEDG1|D1S3362|ECGF1|EDGN1|EDG1|FLJ58121|S1P1

Gene name

sphingosine-1-phosphate receptor 1

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p21

Known cancer genes

Yes

Protein products

EDG1

Sphingosine 1-phosphate receptor 1

Database cross reference

HGNC:3165
MIM:601974
Ensembl:ENSG00000170989
HPRD:03578
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

 

Ontology annotation

GO ID

GO annotation

GO:0001525

angiogenesis

GO:0001619

lysosphingolipid and lysophosphatidic acid receptor activity

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0005886

plasma membrane

GO:0007155

cell adhesion

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

GO:0007420

brain development

GO:0009897

external side of plasma membrane

GO:0016021

integral to membrane

GO:0019226

transmission of nerve impulse

GO:0030155

regulation of cell adhesion

GO:0030182

neuron differentiation

GO:0030335

positive regulation of cell migration

GO:0032320

positive regulation of Ras GTPase activity

GO:0045446

endothelial cell differentiation

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046625

sphingolipid binding

GO:0048661

positive regulation of smooth muscle cell proliferation

GO:0050927

positive regulation of positive chemotaxis

GO:0051482

elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger

GO:0051497

negative regulation of stress fiber assembly