Gene basic information
LiverAtlas Gene ID |
HuLG001355 |
Entrez Gene ID |
|
Official Gene Symbol |
EGF |
Synonyms |
HOMG4|URG |
Gene name |
epidermal growth factor |
Gene Type |
protein-coding |
Chromosome |
4 |
Genomics Location |
4q25 |
Known cancer genes |
Yes |
Protein products |
cDNA FLJ60402, highly similar to Pro-epidermal growth factor |
Related liver disease name |
Liver fibrosis and liver cirrhosis |
Database cross reference |
HGNC:3229
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000186 |
activation of MAPKK activity |
GO:0001525 |
angiogenesis |
GO:0002576 |
platelet degranulation |
GO:0005154 |
epidermal growth factor receptor binding |
GO:0005509 |
calcium ion binding |
GO:0005515 |
protein binding |
GO:0005576 |
extracellular region |
GO:0005615 |
extracellular space |
GO:0005625 |
soluble fraction |
GO:0005886 |
plasma membrane |
GO:0006260 |
DNA replication |
GO:0007165 |
signal transduction |
GO:0007173 |
epidermal growth factor receptor signaling pathway |
GO:0007596 |
blood coagulation |
GO:0008083 |
growth factor activity |
GO:0008284 |
positive regulation of cell proliferation |
GO:0016021 |
integral to membrane |
GO:0021940 |
positive regulation of cerebellar granule cell precursor proliferation |
GO:0030168 |
platelet activation |
GO:0030297 |
transmembrane receptor protein tyrosine kinase activator activity |
GO:0031093 |
platelet alpha granule lumen |
GO:0035413 |
positive regulation of catenin import into nucleus |
GO:0042059 |
negative regulation of epidermal growth factor receptor signaling pathway |
GO:0042327 |
positive regulation of phosphorylation |
GO:0043406 |
positive regulation of MAP kinase activity |
GO:0045741 |
positive regulation of epidermal growth factor receptor activity |
GO:0045840 |
positive regulation of mitosis |
GO:0048754 |
branching morphogenesis of a tube |
GO:0050708 |
regulation of protein secretion |
GO:0050730 |
regulation of peptidyl-tyrosine phosphorylation |
GO:0051048 |
negative regulation of secretion |
GO:0060749 |
mammary gland alveolus development |
GO:0090279 |
regulation of calcium ion import |
GO:2000008 |
regulation of protein localization at cell surface |