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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001362

Entrez Gene ID

1958

Official Gene Symbol

EGR1

Synonyms

AT225|G0S30|KROXN24|NGFINA|TIS8|ZIFN268|ZNF225

Gene name

early growth response 1

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q31.1

Known cancer genes

Yes

Protein products

Early growth response protein 1

Early growth response 1, isoform CRA a

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3238
MIM:128990
Ensembl:ENSG00000120738
HPRD:00549
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0006351

transcription, DNA-dependent

GO:0008270

zinc ion binding

GO:0009749

response to glucose stimulus

GO:0019221

cytokine-mediated signaling pathway

GO:0030217

T cell differentiation

GO:0030509

BMP signaling pathway

GO:0032868

response to insulin stimulus

GO:0033233

regulation of protein sumoylation

GO:0035035

histone acetyltransferase binding

GO:0043565

sequence-specific DNA binding

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046872

metal ion binding

GO:0060337

type I interferon-mediated signaling pathway

GO:0070498

interleukin-1-mediated signaling pathway

GO:0071445

cellular response to protein stimulus

GO:0071480

cellular response to gamma radiation

GO:0071504

cellular response to heparin

GO:0071506

cellular response to mycophenolic acid

GO:0072110

glomerular mesangial cell proliferation

GO:0072303

positive regulation of glomerular metanephric mesangial cell proliferation

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway