Gene basic information
LiverAtlas Gene ID |
HuLG001362 |
Entrez Gene ID |
|
Official Gene Symbol |
EGR1 |
Synonyms |
AT225|G0S30|KROXN24|NGFINA|TIS8|ZIFN268|ZNF225 |
Gene name |
early growth response 1 |
Gene Type |
protein-coding |
Chromosome |
5 |
Genomics Location |
5q31.1 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:3238
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
GO:0003677 |
DNA binding |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
GO:0005515 |
protein binding |
GO:0005622 |
intracellular |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0006351 |
transcription, DNA-dependent |
GO:0008270 |
zinc ion binding |
GO:0009749 |
response to glucose stimulus |
GO:0019221 |
cytokine-mediated signaling pathway |
GO:0030217 |
T cell differentiation |
GO:0030509 |
BMP signaling pathway |
GO:0032868 |
response to insulin stimulus |
GO:0033233 |
regulation of protein sumoylation |
GO:0035035 |
histone acetyltransferase binding |
GO:0043565 |
sequence-specific DNA binding |
GO:0045893 |
positive regulation of transcription, DNA-dependent |
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
GO:0046872 |
metal ion binding |
GO:0060337 |
type I interferon-mediated signaling pathway |
GO:0070498 |
interleukin-1-mediated signaling pathway |
GO:0071445 |
cellular response to protein stimulus |
GO:0071480 |
cellular response to gamma radiation |
GO:0071504 |
cellular response to heparin |
GO:0071506 |
cellular response to mycophenolic acid |
GO:0072110 |
glomerular mesangial cell proliferation |
GO:0072303 |
positive regulation of glomerular metanephric mesangial cell proliferation |
GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |