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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001371

Entrez Gene ID

1969

Official Gene Symbol

EPHA2

Synonyms

ARCC2|ECK

Gene name

EPH receptor A2

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36

Known cancer genes

Yes

Protein products

Soluble EPHA2 variant 1

Ephrin type-A receptor 2

Protein tyrosine kinase

EPHA2 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3386
MIM:176946
Ensembl:ENSG00000142627
HPRD:01494
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001501

skeletal system development

GO:0001568

blood vessel development

GO:0001570

vasculogenesis

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO:0004872

receptor activity

GO:0005003

ephrin receptor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0005925

focal adhesion

GO:0006468

protein phosphorylation

GO:0006915

apoptosis

GO:0007275

multicellular organismal development

GO:0010591

regulation of lamellipodium assembly

GO:0014028

notochord formation

GO:0021915

neural tube development

GO:0030182

neuron differentiation

GO:0031256

leading edge membrane

GO:0032863

activation of Rac GTPase activity

GO:0033628

regulation of cell adhesion mediated by integrin

GO:0035121

tail morphogenesis

GO:0043491

protein kinase B signaling cascade

GO:0043535

regulation of blood vessel endothelial cell migration

GO:0045765

regulation of angiogenesis

GO:0048013

ephrin receptor signaling pathway

GO:0048320

axial mesoderm formation

GO:0051898

negative regulation of protein kinase B signaling cascade

GO:0060035

notochord cell development

GO:0060326

cell chemotaxis

GO:0070848

response to growth factor stimulus

GO:0090004

positive regulation of establishment of protein localization in plasma membrane