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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001400

Entrez Gene ID

2011

Official Gene Symbol

MARK2

Synonyms

EMKN1|EMK1|MGC99619|PARN1|Par1b

Gene name

MAP/microtubule affinity-regulating kinase 2

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q13

Known cancer genes

Yes

Protein products

cDNA FLJ76779, highly similar to Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 1, mRNA

Uncharacterized protein

Serine/threonine-protein kinase MARK2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3332
MIM:600526
Ensembl:ENSG00000072518
HPRD:02753
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000287

magnesium ion binding

GO:0004674

protein serine/threonine kinase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0006468

protein phosphorylation

GO:0006979

response to oxidative stress

GO:0007243

intracellular protein kinase cascade

GO:0007275

multicellular organismal development

GO:0016020

membrane

GO:0030154

cell differentiation

GO:0045197

establishment or maintenance of epithelial cell apical/basal polarity