Gene basic information
| LiverAtlas Gene ID |
HuLG001419 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
EPAS1 |
|
Synonyms |
ECYT4|HIF2A|HLF|MOP2|PASD2|bHLHe73 |
|
Gene name |
endothelial PAS domain protein 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2p21-p16 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ41851 fis, clone NT2RI3003925, highly similar to Endothelial PAS domain-containing protein 1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3374
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001525 |
angiogenesis |
|
GO:0001666 |
response to hypoxia |
|
GO:0003677 |
DNA binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003705 |
sequence-specific enhancer binding RNA polymerase II transcription factor activity |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0004871 |
signal transducer activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005667 |
transcription factor complex |
|
GO:0005737 |
cytoplasm |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006366 |
transcription from RNA polymerase II promoter |
|
GO:0007165 |
signal transduction |
|
GO:0007275 |
multicellular organismal development |
|
GO:0008134 |
transcription factor binding |
|
GO:0030154 |
cell differentiation |
|
GO:0035035 |
histone acetyltransferase binding |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0048625 |
myoblast cell fate commitment |
