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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001440

Entrez Gene ID

2055

Official Gene Symbol

CLN8

Synonyms

C8orf61|EPMR|FLJ39417

Gene name

ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)

Gene Type

protein-coding

Chromosome

8

Genomics Location

8p23

Known cancer genes

Yes

Protein products

Protein CLN8

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:2079
MIM:607837
Ensembl:ENSG00000182372
HPRD:06383
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001306

age-dependent response to oxidative stress

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005793

ER-Golgi intermediate compartment

GO:0006644

phospholipid metabolic process

GO:0006672

ceramide metabolic process

GO:0006869

lipid transport

GO:0007006

mitochondrial membrane organization

GO:0007040

lysosome organization

GO:0007399

nervous system development

GO:0007628

adult walking behavior

GO:0008203

cholesterol metabolic process

GO:0008219

cell death

GO:0008306

associative learning

GO:0008361

regulation of cell size

GO:0008610

lipid biosynthetic process

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0021522

spinal cord motor neuron differentiation

GO:0030163

protein catabolic process

GO:0033116

ER-Golgi intermediate compartment membrane

GO:0035176

social behavior

GO:0043066

negative regulation of apoptosis

GO:0044257

cellular protein catabolic process

GO:0045494

photoreceptor cell maintenance

GO:0045861

negative regulation of proteolysis

GO:0046513

ceramide biosynthetic process

GO:0050881

musculoskeletal movement

GO:0050884

neuromuscular process controlling posture

GO:0050885

neuromuscular process controlling balance

GO:0051348

negative regulation of transferase activity

GO:0051935

glutamate uptake involved in synaptic transmission

GO:0060041

retina development in camera-type eye

GO:0060052

neurofilament cytoskeleton organization