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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001441

Entrez Gene ID

2056

Official Gene Symbol

EPO

Synonyms

EP|MGC138142|MVCD2

Gene name

erythropoietin

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q22

Known cancer genes

Yes

Protein products

Erythropoietin

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:3415
MIM:133170
Ensembl:ENSG00000130427
HPRD:00586
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001666

response to hypoxia

GO:0005128

erythropoietin receptor binding

GO:0005179

hormone activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0007165

signal transduction

GO:0007566

embryo implantation

GO:0007568

aging

GO:0007584

response to nutrient

GO:0008015

blood circulation

GO:0008284

positive regulation of cell proliferation

GO:0009651

response to salt stress

GO:0010766

negative regulation of sodium ion transport

GO:0030218

erythrocyte differentiation

GO:0032413

negative regulation of ion transmembrane transporter activity

GO:0032496

response to lipopolysaccharide

GO:0033189

response to vitamin A

GO:0033574

response to testosterone stimulus

GO:0042523

positive regulation of tyrosine phosphorylation of Stat5 protein

GO:0042541

hemoglobin biosynthetic process

GO:0043066

negative regulation of apoptosis

GO:0043249

erythrocyte maturation

GO:0043499

eukaryotic cell surface binding

GO:0043526

neuroprotection

GO:0043627

response to estrogen stimulus

GO:0045666

positive regulation of neuron differentiation

GO:0045740

positive regulation of DNA replication

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0046579

positive regulation of Ras protein signal transduction

GO:0048678

response to axon injury

GO:0051602

response to electrical stimulus

GO:0055093

response to hyperoxia

GO:0070555

response to interleukin-1

GO:0071474

cellular hyperosmotic response