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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001443

Entrez Gene ID

2058

Official Gene Symbol

EPRS

Synonyms

DKFZp313B047|EARS|GLUPRORS|PARS|QARS|QPRS

Gene name

glutamyl-prolyl-tRNA synthetase

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q41

Known cancer genes

Yes

Protein products

Lutheran blood group

Bifunctional aminoacyl-tRNA synthetase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3418
MIM:138295
Ensembl:ENSG00000136628
HPRD:00703
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003723

RNA binding

GO:0004818

glutamate-tRNA ligase activity

GO:0004827

proline-tRNA ligase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006418

tRNA aminoacylation for protein translation

GO:0006424

glutamyl-tRNA aminoacylation

GO:0006433

prolyl-tRNA aminoacylation

GO:0006461

protein complex assembly

GO:0010467

gene expression

GO:0016874

ligase activity