Gene basic information
| LiverAtlas Gene ID |
HuLG001447 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ERBB2 |
|
Synonyms |
CD340|HERN2|HERN2/neu|HER2|MLN_19|NEU|NGL|TKR1 |
|
Gene name |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) |
|
Gene Type |
protein-coding |
|
Chromosome |
17 |
|
Genomics Location |
17q11.2-q12|17q21.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3430
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001889 |
liver development |
|
GO:0001948 |
glycoprotein binding |
|
GO:0003677 |
DNA binding |
|
GO:0004713 |
protein tyrosine kinase activity |
|
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
|
GO:0004716 |
receptor signaling protein tyrosine kinase activity |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005006 |
epidermal growth factor receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0005902 |
microvillus |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007165 |
signal transduction |
|
GO:0007166 |
cell surface receptor linked signaling pathway |
|
GO:0007167 |
enzyme linked receptor protein signaling pathway |
|
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
GO:0007173 |
epidermal growth factor receptor signaling pathway |
|
GO:0007399 |
nervous system development |
|
GO:0007411 |
axon guidance |
|
GO:0007422 |
peripheral nervous system development |
|
GO:0007507 |
heart development |
|
GO:0007519 |
skeletal muscle tissue development |
|
GO:0007528 |
neuromuscular junction development |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0008045 |
motor axon guidance |
|
GO:0008283 |
cell proliferation |
|
GO:0009925 |
basal plasma membrane |
|
GO:0010001 |
glial cell differentiation |
|
GO:0014065 |
phosphatidylinositol 3-kinase cascade |
|
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
|
GO:0016021 |
integral to membrane |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0016324 |
apical plasma membrane |
|
GO:0019838 |
growth factor binding |
|
GO:0019903 |
protein phosphatase binding |
|
GO:0030879 |
mammary gland development |
|
GO:0031625 |
ubiquitin protein ligase binding |
|
GO:0032570 |
response to progesterone stimulus |
|
GO:0032886 |
regulation of microtubule-based process |
|
GO:0033088 |
negative regulation of immature T cell proliferation in thymus |
|
GO:0042060 |
wound healing |
|
GO:0042493 |
response to drug |
|
GO:0042552 |
myelination |
|
GO:0042802 |
identical protein binding |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043125 |
ErbB-3 class receptor binding |
|
GO:0043219 |
lateral loop |
|
GO:0043235 |
receptor complex |
|
GO:0043406 |
positive regulation of MAP kinase activity |
|
GO:0043410 |
positive regulation of MAPKKK cascade |
|
GO:0043586 |
tongue development |
|
GO:0045121 |
membrane raft |
|
GO:0045211 |
postsynaptic membrane |
|
GO:0045765 |
regulation of angiogenesis |
|
GO:0045785 |
positive regulation of cell adhesion |
|
GO:0046579 |
positive regulation of Ras protein signal transduction |
|
GO:0046777 |
protein autophosphorylation |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0046983 |
protein dimerization activity |
|
GO:0048015 |
phosphatidylinositol-mediated signaling |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0048485 |
sympathetic nervous system development |
|
GO:0048678 |
response to axon injury |
|
GO:0050679 |
positive regulation of epithelial cell proliferation |
|
GO:0051879 |
Hsp90 protein binding |
|
GO:0060056 |
mammary gland involution |
|
GO:0060209 |
estrus |
