Gene basic information
| LiverAtlas Gene ID |
HuLG001448 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ERBB3 |
|
Synonyms |
ErbBN3|HER3|LCCS2|MDANBFN1|MGC88033|cNerbBN3|cNerbB3|erbB3NS|p180NErbB3|p45NsErbB3|p85NsErbB3 |
|
Gene name |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q13 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3431
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0004713 |
protein tyrosine kinase activity |
|
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
|
GO:0004716 |
receptor signaling protein tyrosine kinase activity |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005634 |
nucleus |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007162 |
negative regulation of cell adhesion |
|
GO:0007165 |
signal transduction |
|
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
|
GO:0007409 |
axonogenesis |
|
GO:0007422 |
peripheral nervous system development |
|
GO:0007507 |
heart development |
|
GO:0007519 |
skeletal muscle tissue development |
|
GO:0007623 |
circadian rhythm |
|
GO:0009968 |
negative regulation of signal transduction |
|
GO:0014037 |
Schwann cell differentiation |
|
GO:0014065 |
phosphatidylinositol 3-kinase cascade |
|
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0016324 |
apical plasma membrane |
|
GO:0016328 |
lateral plasma membrane |
|
GO:0019838 |
growth factor binding |
|
GO:0021545 |
cranial nerve development |
|
GO:0030296 |
protein tyrosine kinase activator activity |
|
GO:0032869 |
cellular response to insulin stimulus |
|
GO:0042060 |
wound healing |
|
GO:0042127 |
regulation of cell proliferation |
|
GO:0042476 |
odontogenesis |
|
GO:0042493 |
response to drug |
|
GO:0042803 |
protein homodimerization activity |
|
GO:0043235 |
receptor complex |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0043586 |
tongue development |
|
GO:0045211 |
postsynaptic membrane |
|
GO:0046326 |
positive regulation of glucose import |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0051048 |
negative regulation of secretion |
|
GO:0051402 |
neuron apoptosis |
|
GO:0060056 |
mammary gland involution |
|
GO:0061098 |
positive regulation of protein tyrosine kinase activity |
