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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001449

Entrez Gene ID

2066

Official Gene Symbol

ERBB4

Synonyms

HER4|MGC138404|p180erbB4

Gene name

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q33.3-q34

Known cancer genes

Yes

Protein products

Receptor tyrosine-protein kinase erbB-4

Putative uncharacterized protein ERBB4

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3432
MIM:600543
Ensembl:ENSG00000178568
HPRD:02767
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO:0004716

receptor signaling protein tyrosine kinase activity

GO:0004872

receptor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005901

caveola

GO:0006355

regulation of transcription, DNA-dependent

GO:0006468

protein phosphorylation

GO:0007165

signal transduction

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

GO:0007507

heart development

GO:0008283

cell proliferation

GO:0014069

postsynaptic density

GO:0016021

integral to membrane

GO:0016323

basolateral plasma membrane

GO:0021537

telencephalon development

GO:0030335

positive regulation of cell migration

GO:0030879

mammary gland development

GO:0032230

positive regulation of synaptic transmission, GABAergic

GO:0032570

response to progesterone stimulus

GO:0042476

odontogenesis

GO:0042493

response to drug

GO:0042542

response to hydrogen peroxide

GO:0043129

surfactant homeostasis

GO:0045165

cell fate commitment

GO:0045768

positive regulation of anti-apoptosis

GO:0046326

positive regulation of glucose import

GO:0050679

positive regulation of epithelial cell proliferation

GO:0060074

synapse maturation