HuLG001455

Entrez Gene ID

2072

Official Gene Symbol

ERCC4

Synonyms

ERCC11|RAD1|XPF

Gene name

excision repair cross-complementing rodent repair deficiency, complementation group 4

Gene Type

protein-coding

Chromosome

16

Genomics Location

16p13.12

Known cancer genes

Yes

Protein products

ERCC4 protein

ERCC4 protein

Uncharacterized protein

DNA repair endonuclease XPF

Database cross reference

HGNC:3436
MIM:133520
Ensembl:ENSG00000175595
HPRD:00594
RefSeq Genomic nucleotide accession:AC_000059
RefSeq Genomic nucleotide gi:89161194

GO annotation

GO:0000014

single-stranded DNA specific endodeoxyribonuclease activity

GO:0000109

nucleotide-excision repair complex

GO:0000110

nucleotide-excision repair factor 1 complex

GO:0000710

meiotic mismatch repair

GO:0000712

resolution of meiotic recombination intermediates

GO:0000718

nucleotide-excision repair, DNA damage removal

GO:0000723

telomere maintenance

GO:0000724

double-strand break repair via homologous recombination

GO:0000781

chromosome, telomeric region

GO:0000784

nuclear chromosome, telomeric region

GO:0003684

damaged DNA binding

GO:0003697

single-stranded DNA binding

GO:0004520

endodeoxyribonuclease activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006281

DNA repair

GO:0006283

transcription-coupled nucleotide-excision repair

GO:0006289

nucleotide-excision repair

GO:0006295

nucleotide-excision repair, DNA incision, 3'-to lesion

GO:0006296

nucleotide-excision repair, DNA incision, 5'-to lesion

GO:0008022

protein C-terminus binding

GO:0009411

response to UV

GO:0009650

UV protection

GO:0010834

telomere maintenance via telomere shortening

GO:0016787

hydrolase activity

GO:0032205

negative regulation of telomere maintenance

GO:0033683

nucleotide-excision repair, DNA incision

GO:0043566

structure-specific DNA binding

GO:0047485

protein N-terminus binding