HuLG001457

Entrez Gene ID

2074

Official Gene Symbol

ERCC6

Synonyms

ARMD5|CKN2|COFS|COFS1|CSB|RAD26

Gene name

excision repair cross-complementing rodent repair deficiency, complementation group 6

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q11.23

Known cancer genes

Yes

Protein products

Excision repair cross-complementing rodent repair deficiency, complementation group 6

DNA excision repair protein ERCC-6

Database cross reference

HGNC:3438
MIM:609413
Ensembl:ENSG00000225830
HPRD:00596
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

GO annotation

GO:0000166

nucleotide binding

GO:0000303

response to superoxide

GO:0003677

DNA binding

GO:0003678

DNA helicase activity

GO:0003682

chromatin binding

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005625

soluble fraction

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005730

nucleolus

GO:0006281

DNA repair

GO:0006283

transcription-coupled nucleotide-excision repair

GO:0006284

base-excision repair

GO:0006289

nucleotide-excision repair

GO:0006290

pyrimidine dimer repair

GO:0006355

regulation of transcription, DNA-dependent

GO:0006366

transcription from RNA polymerase II promoter

GO:0006979

response to oxidative stress

GO:0007256

activation of JNKK activity

GO:0007257

activation of JUN kinase activity

GO:0008022

protein C-terminus binding

GO:0008023

transcription elongation factor complex

GO:0008094

DNA-dependent ATPase activity

GO:0008630

DNA damage response, signal transduction resulting in induction of apoptosis

GO:0009411

response to UV

GO:0009636

response to toxin

GO:0010165

response to X-ray

GO:0010224

response to UV-B

GO:0010332

response to gamma radiation

GO:0016787

hydrolase activity

GO:0032403

protein complex binding

GO:0032786

positive regulation of transcription elongation, DNA-dependent

GO:0045494

photoreceptor cell maintenance

GO:0047485

protein N-terminus binding