Gene basic information
| LiverAtlas Gene ID |
HuLG001464 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ESR1 |
|
Synonyms |
DKFZp686N23123|ER|ESR|ESRA|Era|NR3A1 |
|
Gene name |
estrogen receptor 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
6 |
|
Genomics Location |
6q25.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis B infection |
|
Database cross reference |
HGNC:3467
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001547 |
antral ovarian follicle growth |
|
GO:0002064 |
epithelial cell development |
|
GO:0002076 |
osteoblast development |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003707 |
steroid hormone receptor activity |
|
GO:0005496 |
steroid binding |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006355 |
regulation of transcription, DNA-dependent |
|
GO:0007165 |
signal transduction |
|
GO:0008013 |
beta-catenin binding |
|
GO:0008134 |
transcription factor binding |
|
GO:0008209 |
androgen metabolic process |
|
GO:0008270 |
zinc ion binding |
|
GO:0008584 |
male gonad development |
|
GO:0010467 |
gene expression |
|
GO:0016020 |
membrane |
|
GO:0016585 |
chromatin remodeling complex |
|
GO:0019899 |
enzyme binding |
|
GO:0030235 |
nitric-oxide synthase regulator activity |
|
GO:0030284 |
estrogen receptor activity |
|
GO:0030315 |
T-tubule |
|
GO:0030520 |
estrogen receptor signaling pathway |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032403 |
protein complex binding |
|
GO:0034056 |
estrogen response element binding |
|
GO:0034339 |
regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor |
|
GO:0042562 |
hormone binding |
|
GO:0043005 |
neuron projection |
|
GO:0043195 |
terminal button |
|
GO:0043204 |
perikaryon |
|
GO:0043401 |
steroid hormone mediated signaling pathway |
|
GO:0043526 |
neuroprotection |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0043627 |
response to estrogen stimulus |
|
GO:0045885 |
positive regulation of survival gene product expression |
|
GO:0046872 |
metal ion binding |
|
GO:0048146 |
positive regulation of fibroblast proliferation |
|
GO:0048386 |
positive regulation of retinoic acid receptor signaling pathway |
|
GO:0060065 |
uterus development |
|
GO:0060068 |
vagina development |
|
GO:0060523 |
prostate epithelial cord elongation |
|
GO:0060527 |
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis |
|
GO:0060687 |
regulation of branching involved in prostate gland morphogenesis |
|
GO:0060745 |
mammary gland branching involved in pregnancy |
|
GO:0060749 |
mammary gland alveolus development |
|
GO:0060750 |
epithelial cell proliferation involved in mammary gland duct elongation |
