Gene basic information
| LiverAtlas Gene ID |
HuLG001472 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ETFDH |
|
Synonyms |
ETFQO|MADD |
|
Gene name |
electron-transferring-flavoprotein dehydrogenase |
|
Gene Type |
protein-coding |
|
Chromosome |
4 |
|
Genomics Location |
4q32-q35 |
|
Known cancer genes |
Yes |
|
Protein products |
Mutant electron-transferring flavoprotein dehydrogenase Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3483
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004174 |
electron-transferring-flavoprotein dehydrogenase activity |
|
GO:0005739 |
mitochondrion |
|
GO:0005743 |
mitochondrial inner membrane |
|
GO:0005759 |
mitochondrial matrix |
|
GO:0006810 |
transport |
|
GO:0006979 |
response to oxidative stress |
|
GO:0009055 |
electron carrier activity |
|
GO:0016020 |
membrane |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0022900 |
electron transport chain |
|
GO:0022904 |
respiratory electron transport chain |
|
GO:0031305 |
integral to mitochondrial inner membrane |
|
GO:0031966 |
mitochondrial membrane |
|
GO:0033539 |
fatty acid beta-oxidation using acyl-CoA dehydrogenase |
|
GO:0043783 |
oxidoreductase activity, oxidizing metal ions with flavin as acceptor |
|
GO:0046872 |
metal ion binding |
|
GO:0048038 |
quinone binding |
|
GO:0048039 |
ubiquinone binding |
|
GO:0050660 |
flavin adenine dinucleotide binding |
|
GO:0051539 |
4 iron, 4 sulfur cluster binding |
