HuLG001473

Entrez Gene ID

2113

Official Gene Symbol

ETS1

Synonyms

ETSN1|EWSR2|FLJ10768

Gene name

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

Gene Type

protein-coding

Chromosome

11

Genomics Location

11q23.3

Known cancer genes

Yes

Protein products

cDNA FLJ75737, highly similar to Homo sapiens v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), mRNA

cDNA FLJ59231, highly similar to C-ets-1 protein

Protein C-ets-1

Putative uncharacterized protein DKFZp686D0662

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3488
MIM:164720
Ensembl:ENSG00000134954
HPRD:01260
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0003677

DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0006351

transcription, DNA-dependent

GO:0006366

transcription from RNA polymerase II promoter

GO:0006917

induction of apoptosis

GO:0006955

immune response

GO:0008134

transcription factor binding

GO:0008285

negative regulation of cell proliferation

GO:0030578

PML body organization

GO:0043565

sequence-specific DNA binding

GO:0045648

positive regulation of erythrocyte differentiation

GO:0045786

negative regulation of cell cycle

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046677

response to antibiotic

GO:0048870

cell motility

GO:0051272

positive regulation of cellular component movement