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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001500

Entrez Gene ID

2150

Official Gene Symbol

F2RL1

Synonyms

GPR11|PAR2

Gene name

coagulation factor II (thrombin) receptor-like 1

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q13

Known cancer genes

Yes

Protein products

Proteinase-activated receptor 2

Coagulation factor II (Thrombin) receptor-like 1

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:3538
MIM:600933
Ensembl:ENSG00000164251
HPRD:02960
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002690

positive regulation of leukocyte chemotaxis

GO:0004872

receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0005102

receptor binding

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0007204

elevation of cytosolic calcium ion concentration

GO:0015057

thrombin receptor activity

GO:0030193

regulation of blood coagulation

GO:0050927

positive regulation of positive chemotaxis