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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001502

Entrez Gene ID

2152

Official Gene Symbol

F3

Synonyms

CD142|FLJ17960|TF|TFA

Gene name

coagulation factor III (thromboplastin, tissue factor)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p22-p21

Known cancer genes

Yes

Protein products

Tissue factor

Tissue factor

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis C

Chronic hepatitis C

Chronic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:3541
MIM:134390
Ensembl:ENSG00000117525
HPRD:00603
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001938

positive regulation of endothelial cell proliferation

GO:0002020

protease binding

GO:0002541

activation of plasma proteins involved in acute inflammatory response

GO:0002543

activation of blood coagulation via clotting cascade

GO:0005543

phospholipid binding

GO:0005615

extracellular space

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0006916

anti-apoptosis

GO:0006919

activation of caspase activity

GO:0007568

aging

GO:0007596

blood coagulation

GO:0007598

blood coagulation, extrinsic pathway

GO:0009266

response to temperature stimulus

GO:0009611

response to wounding

GO:0009612

response to mechanical stimulus

GO:0009986

cell surface

GO:0010641

positive regulation of platelet-derived growth factor receptor signaling pathway

GO:0014911

positive regulation of smooth muscle cell migration

GO:0016021

integral to membrane

GO:0030335

positive regulation of cell migration

GO:0031012

extracellular matrix

GO:0031233

intrinsic to external side of plasma membrane

GO:0032355

response to estradiol stimulus

GO:0032496

response to lipopolysaccharide

GO:0034405

response to fluid shear stress

GO:0043498

cell surface binding

GO:0045766

positive regulation of angiogenesis

GO:0050927

positive regulation of positive chemotaxis

GO:0051897

positive regulation of protein kinase B signaling cascade

GO:0055098

response to low-density lipoprotein particle stimulus

GO:0070301

cellular response to hydrogen peroxide