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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001524

Entrez Gene ID

2180

Official Gene Symbol

ACSL1

Synonyms

ACS1|FACL1|FACL2|LACS|LACS1|LACS2

Gene name

acyl-CoA synthetase long-chain family member 1

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q35

Known cancer genes

Yes

Protein products

Long-chain-fatty-acid--CoA ligase 1

Acyl-CoA synthetase long-chain family member 1 isoform a

Acyl-CoA synthetase long-chain family member 1 isoform c

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3569
MIM:152425
Ensembl:ENSG00000151726
HPRD:01068
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0004467

long-chain fatty acid-CoA ligase activity

GO:0005524

ATP binding

GO:0005739

mitochondrion

GO:0005741

mitochondrial outer membrane

GO:0005777

peroxisome

GO:0005778

peroxisomal membrane

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0006631

fatty acid metabolic process

GO:0007586

digestion

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016874

ligase activity

GO:0019432

triglyceride biosynthetic process

GO:0035338

long-chain fatty-acyl-CoA biosynthetic process

GO:0044255

cellular lipid metabolic process

GO:0046320

regulation of fatty acid oxidation