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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001525

Entrez Gene ID

2181

Official Gene Symbol

ACSL3

Synonyms

ACS3|FACL3|PRO2194

Gene name

acyl-CoA synthetase long-chain family member 3

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q34-q35

Known cancer genes

Yes

Protein products

Long-chain-fatty-acid--CoA ligase 3

cDNA FLJ10609 fis, clone NT2RP2005276, highly similar to Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3)

ACSL3 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3570
MIM:602371
Ensembl:ENSG00000123983
HPRD:03845
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0004321

fatty-acyl-CoA synthase activity

GO:0004467

long-chain fatty acid-CoA ligase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005739

mitochondrion

GO:0005741

mitochondrial outer membrane

GO:0005777

peroxisome

GO:0005778

peroxisomal membrane

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0006633

fatty acid biosynthetic process

GO:0007420

brain development

GO:0007584

response to nutrient

GO:0014070

response to organic cyclic compound

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016874

ligase activity

GO:0019432

triglyceride biosynthetic process

GO:0035338

long-chain fatty-acyl-CoA biosynthetic process

GO:0044255

cellular lipid metabolic process