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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001526

Entrez Gene ID

2182

Official Gene Symbol

ACSL4

Synonyms

ACS4|FACL4|LACS4|MRX63|MRX68

Gene name

acyl-CoA synthetase long-chain family member 4

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xq22.3-q23

Known cancer genes

Yes

Protein products

Long-chain-fatty-acid--CoA ligase 4

Acyl-CoA synthetase long-chain family member 4

Acyl-CoA synthetase 4

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3571
MIM:300157
Ensembl:ENSG00000068366
HPRD:02152
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0004467

long-chain fatty acid-CoA ligase activity

GO:0005524

ATP binding

GO:0005739

mitochondrion

GO:0005741

mitochondrial outer membrane

GO:0005777

peroxisome

GO:0005778

peroxisomal membrane

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0006629

lipid metabolic process

GO:0006631

fatty acid metabolic process

GO:0007584

response to nutrient

GO:0007611

learning or memory

GO:0015908

fatty acid transport

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016874

ligase activity

GO:0019432

triglyceride biosynthetic process

GO:0035338

long-chain fatty-acyl-CoA biosynthetic process

GO:0043025

neuronal cell body

GO:0044255

cellular lipid metabolic process

GO:0060136

embryonic process involved in female pregnancy

GO:0060996

dendritic spine development

GO:0070672

response to interleukin-15