HuLG001536

Entrez Gene ID

2194

Official Gene Symbol

FASN

Synonyms

FAS|MGC14367|MGC15706|OAN519|SDR27X1

Gene name

fatty acid synthase

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q25

Known cancer genes

Yes

Protein products

Fatty acid synthase

FASN protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3594
MIM:600212
Ensembl:ENSG00000169710
HPRD:02567
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000036

acyl carrier activity

GO:0004312

fatty acid synthase activity

GO:0004313

[acyl-carrier-protein] S-acetyltransferase activity

GO:0004314

[acyl-carrier-protein] S-malonyltransferase activity

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

GO:0004316

3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity

GO:0004317

3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity

GO:0004319

enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity

GO:0004320

oleoyl-[acyl-carrier-protein] hydrolase activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006112

energy reserve metabolic process

GO:0006631

fatty acid metabolic process

GO:0006633

fatty acid biosynthetic process

GO:0006766

vitamin metabolic process

GO:0006767

water-soluble vitamin metabolic process

GO:0008270

zinc ion binding

GO:0015939

pantothenate metabolic process

GO:0016295

myristoyl-[acyl-carrier-protein] hydrolase activity

GO:0016296

palmitoyl-[acyl-carrier-protein] hydrolase activity

GO:0016491

oxidoreductase activity

GO:0016740

transferase activity

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

GO:0016788

hydrolase activity, acting on ester bonds

GO:0016829

lyase activity

GO:0019432

triglyceride biosynthetic process

GO:0031177

phosphopantetheine binding

GO:0031325

positive regulation of cellular metabolic process

GO:0035338

long-chain fatty-acyl-CoA biosynthetic process

GO:0042470

melanosome

GO:0042587

glycogen granule

GO:0044255

cellular lipid metabolic process

GO:0048037

cofactor binding