Gene basic information
| LiverAtlas Gene ID |
HuLG001541 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
FBN1 |
|
Synonyms |
FBN|MASS|MFS1|OCTD|SGS|SSKS|WMS |
|
Gene name |
fibrillin 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
15 |
|
Genomics Location |
15q21.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3603
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001501 |
skeletal system development |
|
GO:0001527 |
microfibril |
|
GO:0005201 |
extracellular matrix structural constituent |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005578 |
proteinaceous extracellular matrix |
|
GO:0005604 |
basement membrane |
|
GO:0005615 |
extracellular space |
|
GO:0007507 |
heart development |
|
GO:0031012 |
extracellular matrix |
|
GO:0035582 |
negative regulation of BMP signaling pathway by extracellular sequestering of BMP |
|
GO:0035583 |
negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta |
