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Gene basic information

LiverAtlas Gene ID

HuLG001564

Entrez Gene ID

2235

Official Gene Symbol

FECH

Synonyms

EPP|FCE

Gene name

ferrochelatase

Gene Type

protein-coding

Chromosome

18

Genomics Location

18q21.3

Known cancer genes

Yes

Protein products

Ferrochelatase, mitochondrial

Ferrochelatase

Ferrochelatase

Related liver disease name

Erythropoietic protoporphyria

Database cross reference

HGNC:3647
MIM:612386
Ensembl:ENSG00000066926
HPRD:01509
RefSeq Genomic nucleotide accession:AC_000061
RefSeq Genomic nucleotide gi:89161196

 

Ontology annotation

GO ID

GO annotation

GO:0004325

ferrochelatase activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0005759

mitochondrial matrix

GO:0006091

generation of precursor metabolites and energy

GO:0006778

porphyrin metabolic process

GO:0006783

heme biosynthetic process

GO:0008198

ferrous iron binding

GO:0009416

response to light stimulus

GO:0016020

membrane

GO:0046501

protoporphyrinogen IX metabolic process

GO:0046872

metal ion binding

GO:0051537

2 iron, 2 sulfur cluster binding