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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001569

Entrez Gene ID

2243

Official Gene Symbol

FGA

Synonyms

Fib2|MGC119422|MGC119423|MGC119425

Gene name

fibrinogen alpha chain

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q28

Known cancer genes

Yes

Protein products

Fibrinogen alpha chain

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:3661
MIM:134820
Ensembl:ENSG00000171560
HPRD:00619
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002576

platelet degranulation

GO:0005102

receptor binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005577

fibrinogen complex

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0007165

signal transduction

GO:0007596

blood coagulation

GO:0009897

external side of plasma membrane

GO:0030168

platelet activation

GO:0030674

protein binding, bridging

GO:0031091

platelet alpha granule

GO:0031093

platelet alpha granule lumen

GO:0043499

eukaryotic cell surface binding

GO:0051258

protein polymerization

GO:0051592

response to calcium ion