HuLG001571

Entrez Gene ID

2245

Official Gene Symbol

FGD1

Synonyms

AAS|FGDY|MRXS16|ZFYVE3

Gene name

FYVE, RhoGEF and PH domain containing 1

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xp11.21

Known cancer genes

Yes

Protein products

FYVE, RhoGEF and PH domain-containing protein 1

Database cross reference

HGNC:3663
MIM:300546
Ensembl:ENSG00000102302
HPRD:02373
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

GO annotation

GO:0001726

ruffle

GO:0005085

guanyl-nucleotide exchange factor activity

GO:0005089

Rho guanyl-nucleotide exchange factor activity

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005794

Golgi apparatus

GO:0005829

cytosol

GO:0005856

cytoskeleton

GO:0005886

plasma membrane

GO:0006915

apoptosis

GO:0007010

cytoskeleton organization

GO:0007165

signal transduction

GO:0007264

small GTPase mediated signal transduction

GO:0007275

multicellular organismal development

GO:0008360

regulation of cell shape

GO:0008624

induction of apoptosis by extracellular signals

GO:0009887

organ morphogenesis

GO:0030027

lamellipodium

GO:0030036

actin cytoskeleton organization

GO:0031267

small GTPase binding

GO:0035023

regulation of Rho protein signal transduction

GO:0043088

regulation of Cdc42 GTPase activity

GO:0046847

filopodium assembly

GO:0046872

metal ion binding

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051056

regulation of small GTPase mediated signal transduction