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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001572

Entrez Gene ID

2246

Official Gene Symbol

FGF1

Synonyms

AFGF|ECGF|ECGFNbeta|ECGFA|ECGFB|FGFNalpha|FGFA|GLIO703|HBGF1

Gene name

fibroblast growth factor 1 (acidic)

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q31

Known cancer genes

Yes

Protein products

Uncharacterized protein

Uncharacterized protein

Heparin-binding growth factor 1

Acidic fibroblast growth factor

Acidic fibroblast growth factor

Acid fibroblast growth factor-like protein

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:3665
MIM:131220
Ensembl:ENSG00000113578
HPRD:00567
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001759

organ induction

GO:0001934

positive regulation of protein phosphorylation

GO:0005104

fibroblast growth factor receptor binding

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005578

proteinaceous extracellular matrix

GO:0005615

extracellular space

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005938

cell cortex

GO:0007165

signal transduction

GO:0007275

multicellular organismal development

GO:0007399

nervous system development

GO:0008083

growth factor activity

GO:0008201

heparin binding

GO:0008284

positive regulation of cell proliferation

GO:0008286

insulin receptor signaling pathway

GO:0008543

fibroblast growth factor receptor signaling pathway

GO:0009653

anatomical structure morphogenesis

GO:0010740

positive regulation of intracellular protein kinase cascade

GO:0030154

cell differentiation

GO:0030324

lung development

GO:0030335

positive regulation of cell migration

GO:0034605

cellular response to heat

GO:0045542

positive regulation of cholesterol biosynthetic process

GO:0045766

positive regulation of angiogenesis

GO:0045785

positive regulation of cell adhesion

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048155

S100 alpha binding

GO:0050679

positive regulation of epithelial cell proliferation

GO:0051781

positive regulation of cell division