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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001586

Entrez Gene ID

2260

Official Gene Symbol

FGFR1

Synonyms

BFGFR|CD331|CEK|FGFBR|FGFRN1|FLG|FLJ99988|FLTN2|FLT2|HBGFR|KAL2|NNSAM|OGD|bFGFNRN1

Gene name

fibroblast growth factor receptor 1

Gene Type

protein-coding

Chromosome

8

Genomics Location

8p12

Known cancer genes

Yes

Protein products

Soluble FGFR1 variant 1

Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA b

Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA f

Uncharacterized protein

Uncharacterized protein

Basic fibroblast growth factor receptor 1

Fibroblast growth factor receptor 1 isoform 1 variant

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3688
MIM:136350
Ensembl:ENSG00000077782
HPRD:00634
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000165

MAPKKK cascade

GO:0000166

nucleotide binding

GO:0001501

skeletal system development

GO:0004713

protein tyrosine kinase activity

GO:0004872

receptor activity

GO:0005007

fibroblast growth factor receptor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005576

extracellular region

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006468

protein phosphorylation

GO:0007411

axon guidance

GO:0008201

heparin binding

GO:0008284

positive regulation of cell proliferation

GO:0008286

insulin receptor signaling pathway

GO:0008543

fibroblast growth factor receptor signaling pathway

GO:0016021

integral to membrane

GO:0016049

cell growth

GO:0042803

protein homodimerization activity