Gene basic information
| LiverAtlas Gene ID |
HuLG001589 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
FGFR2 |
|
Synonyms |
BEK|BFRN1|CD332|CEK3|CFD1|ECT1|FLJ98662|JWS|KNSAM|KGFR|TK14|TK25 |
|
Gene name |
fibroblast growth factor receptor 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
10 |
|
Genomics Location |
10q26 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ61222, highly similar to Fibroblast growth factor receptor 2 (EC 2.7.10.1) Fibroblast growth factor receptor 2 variant |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3689
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0000166 |
nucleotide binding |
|
GO:0001525 |
angiogenesis |
|
GO:0001657 |
ureteric bud development |
|
GO:0001701 |
in utero embryonic development |
|
GO:0002053 |
positive regulation of mesenchymal cell proliferation |
|
GO:0003148 |
outflow tract septum morphogenesis |
|
GO:0003149 |
membranous septum morphogenesis |
|
GO:0004713 |
protein tyrosine kinase activity |
|
GO:0004872 |
receptor activity |
|
GO:0005007 |
fibroblast growth factor receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005576 |
extracellular region |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0005938 |
cell cortex |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007409 |
axonogenesis |
|
GO:0008201 |
heparin binding |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0008543 |
fibroblast growth factor receptor signaling pathway |
|
GO:0008589 |
regulation of smoothened signaling pathway |
|
GO:0009791 |
post-embryonic development |
|
GO:0009880 |
embryonic pattern specification |
|
GO:0009887 |
organ morphogenesis |
|
GO:0009986 |
cell surface |
|
GO:0010453 |
regulation of cell fate commitment |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0016049 |
cell growth |
|
GO:0016331 |
morphogenesis of embryonic epithelium |
|
GO:0017134 |
fibroblast growth factor binding |
|
GO:0021769 |
orbitofrontal cortex development |
|
GO:0021847 |
ventricular zone neuroblast division |
|
GO:0021860 |
pyramidal neuron development |
|
GO:0022612 |
gland morphogenesis |
|
GO:0030177 |
positive regulation of Wnt receptor signaling pathway |
|
GO:0030282 |
bone mineralization |
|
GO:0030324 |
lung development |
|
GO:0030855 |
epithelial cell differentiation |
|
GO:0030901 |
midbrain development |
|
GO:0030916 |
otic vesicle formation |
|
GO:0031012 |
extracellular matrix |
|
GO:0031069 |
hair follicle morphogenesis |
|
GO:0032808 |
lacrimal gland development |
|
GO:0035264 |
multicellular organism growth |
|
GO:0035265 |
organ growth |
|
GO:0035602 |
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow |
|
GO:0035603 |
fibroblast growth factor receptor signaling pathway involved in hemopoiesis |
|
GO:0035604 |
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow |
|
GO:0035607 |
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development |
|
GO:0040014 |
regulation of multicellular organism growth |
|
GO:0040036 |
regulation of fibroblast growth factor receptor signaling pathway |
|
GO:0042472 |
inner ear morphogenesis |
|
GO:0042476 |
odontogenesis |
|
GO:0045165 |
cell fate commitment |
|
GO:0045787 |
positive regulation of cell cycle |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0048286 |
lung alveolus development |
|
GO:0048557 |
embryonic digestive tract morphogenesis |
|
GO:0048562 |
embryonic organ morphogenesis |
|
GO:0048565 |
digestive tract development |
|
GO:0048568 |
embryonic organ development |
|
GO:0048608 |
reproductive structure development |
|
GO:0048730 |
epidermis morphogenesis |
|
GO:0048755 |
branching morphogenesis of a nerve |
|
GO:0048762 |
mesenchymal cell differentiation |
|
GO:0050679 |
positive regulation of epithelial cell proliferation |
|
GO:0051150 |
regulation of smooth muscle cell differentiation |
|
GO:0051781 |
positive regulation of cell division |
|
GO:0055010 |
ventricular cardiac muscle tissue morphogenesis |
|
GO:0060045 |
positive regulation of cardiac muscle cell proliferation |
|
GO:0060076 |
excitatory synapse |
|
GO:0060174 |
limb bud formation |
|
GO:0060348 |
bone development |
|
GO:0060349 |
bone morphogenesis |
|
GO:0060442 |
branching involved in prostate gland morphogenesis |
|
GO:0060445 |
branching involved in salivary gland morphogenesis |
|
GO:0060449 |
bud elongation involved in lung branching |
|
GO:0060463 |
lung lobe morphogenesis |
|
GO:0060484 |
lung-associated mesenchyme development |
|
GO:0060501 |
positive regulation of epithelial cell proliferation involved in lung morphogenesis |
|
GO:0060512 |
prostate gland morphogenesis |
|
GO:0060523 |
prostate epithelial cord elongation |
|
GO:0060527 |
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis |
|
GO:0060529 |
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development |
|
GO:0060595 |
fibroblast growth factor receptor signaling pathway involved in mammary gland specification |
|
GO:0060601 |
lateral sprouting from an epithelium |
|
GO:0060615 |
mammary gland bud formation |
|
GO:0060664 |
epithelial cell proliferation involved in salivary gland morphogenesis |
|
GO:0060667 |
branch elongation involved in salivary gland morphogenesis |
|
GO:0060670 |
branching involved in embryonic placenta morphogenesis |
|
GO:0060687 |
regulation of branching involved in prostate gland morphogenesis |
|
GO:0060688 |
regulation of morphogenesis of a branching structure |
|
GO:0060915 |
mesenchymal cell differentiation involved in lung development |
|
GO:0060916 |
mesenchymal cell proliferation involved in lung development |
|
GO:0070372 |
regulation of ERK1 and ERK2 cascade |
|
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
|
GO:0071445 |
cellular response to protein stimulus |
|
GO:0090263 |
positive regulation of canonical Wnt receptor signaling pathway |
