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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001590

Entrez Gene ID

2264

Official Gene Symbol

FGFR4

Synonyms

CD334|JTK2|MGC20292|TKF

Gene name

fibroblast growth factor receptor 4

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q35.1-qter

Known cancer genes

Yes

Protein products

Fibroblast growth factor receptor 4

Fibroblast growth factor receptor 4 variant

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:3691
MIM:134935
Ensembl:ENSG00000160867
HPRD:00625
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001759

organ induction

GO:0004713

protein tyrosine kinase activity

GO:0004872

receptor activity

GO:0005007

fibroblast growth factor receptor activity

GO:0005524

ATP binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006468

protein phosphorylation

GO:0008284

positive regulation of cell proliferation

GO:0008286

insulin receptor signaling pathway

GO:0008543

fibroblast growth factor receptor signaling pathway

GO:0017134

fibroblast growth factor binding

GO:0030324

lung development