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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001594

Entrez Gene ID

2271

Official Gene Symbol

FH

Synonyms

HLRCC|LRCC|MCL|MCUL1

Gene name

fumarate hydratase

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q42.1

Known cancer genes

Yes

Protein products

Fumarate hydratase

Fumarate hydratase, mitochondrial

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:3700
MIM:136850
Ensembl:ENSG00000091483
HPRD:00652
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004333

fumarate hydratase activity

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0006099

tricarboxylic acid cycle

GO:0006106

fumarate metabolic process

GO:0006108

malate metabolic process

GO:0016829

lyase activity

GO:0030054

cell junction

GO:0045239

tricarboxylic acid cycle enzyme complex

GO:0048873

homeostasis of number of cells within a tissue