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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001595

Entrez Gene ID

2272

Official Gene Symbol

FHIT

Synonyms

AP3Aase|FRA3B

Gene name

fragile histidine triad gene

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p14.2

Known cancer genes

Yes

Protein products

FHIT

Truncated FHIT

FHIT

cDNA FLJ75908, highly similar to Homo sapiens fragile histidine triad gene (FHIT), mRNA

Bis(5'-adenosyl)-triphosphatase

Diadenosine triphosphate hydrolase

Diadenosine triphosphate hydrolase

Fragile histidine triad

FHIT

FHIT

Diadenosine triphosphate hydroxylase

Fragile histidine triad

Diadenosine triphosphate hydrolase

Related liver disease name

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:3701
MIM:601153
Ensembl:ENSG00000189283
HPRD:03096
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003824

catalytic activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0006260

DNA replication

GO:0009117

nucleotide metabolic process

GO:0015964

diadenosine triphosphate catabolic process

GO:0016151

nickel ion binding

GO:0016787

hydrolase activity

GO:0043231

intracellular membrane-bounded organelle

GO:0047710

bis(5'-adenosyl)-triphosphatase activity