Gene basic information
LiverAtlas Gene ID |
HuLG001595 |
Entrez Gene ID |
|
Official Gene Symbol |
FHIT |
Synonyms |
AP3Aase|FRA3B |
Gene name |
fragile histidine triad gene |
Gene Type |
protein-coding |
Chromosome |
3 |
Genomics Location |
3p14.2 |
Known cancer genes |
Yes |
Protein products |
cDNA FLJ75908, highly similar to Homo sapiens fragile histidine triad gene (FHIT), mRNA Bis(5'-adenosyl)-triphosphatase Diadenosine triphosphate hydrolase Diadenosine triphosphate hydrolase |
Related liver disease name |
|
Database cross reference |
HGNC:3701
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0003824 |
catalytic activity |
GO:0005515 |
protein binding |
GO:0005634 |
nucleus |
GO:0005737 |
cytoplasm |
GO:0005829 |
cytosol |
GO:0005886 |
plasma membrane |
GO:0006260 |
DNA replication |
GO:0009117 |
nucleotide metabolic process |
GO:0015964 |
diadenosine triphosphate catabolic process |
GO:0016151 |
nickel ion binding |
GO:0016787 |
hydrolase activity |
GO:0043231 |
intracellular membrane-bounded organelle |
GO:0047710 |
bis(5'-adenosyl)-triphosphatase activity |