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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001621

Entrez Gene ID

2308

Official Gene Symbol

FOXO1

Synonyms

FKH1|FKHR|FOXO1A

Gene name

forkhead box O1

Gene Type

protein-coding

Chromosome

13

Genomics Location

13q14.1

Known cancer genes

Yes

Protein products

Forkhead box protein O1

Related liver disease name

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Database cross reference

HGNC:3819
MIM:136533
Ensembl:ENSG00000150907
HPRD:00645
RefSeq Genomic nucleotide accession:AC_000056
RefSeq Genomic nucleotide gi:89161191

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001568

blood vessel development

GO:0003690

double-stranded DNA binding

GO:0003705

sequence-specific enhancer binding RNA polymerase II transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006916

anti-apoptosis

GO:0006974

response to DNA damage stimulus

GO:0007389

pattern specification process

GO:0008134

transcription factor binding

GO:0008286

insulin receptor signaling pathway

GO:0008301

DNA bending activity

GO:0009790

embryo development

GO:0009888

tissue development

GO:0019901

protein kinase binding

GO:0031018

endocrine pancreas development

GO:0032873

negative regulation of stress-activated MAPK cascade

GO:0042127

regulation of cell proliferation

GO:0043565

sequence-specific DNA binding

GO:0045722

positive regulation of gluconeogenesis

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0048011

nerve growth factor receptor signaling pathway

GO:0048015

phosphatidylinositol-mediated signaling

GO:0048513

organ development

GO:0051090

regulation of sequence-specific DNA binding transcription factor activity