Gene basic information
LiverAtlas Gene ID |
HuLG001632 |
Entrez Gene ID |
|
Official Gene Symbol |
FLT1 |
Synonyms |
FLT|VEGFR1 |
Gene name |
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) |
Gene Type |
protein-coding |
Chromosome |
13 |
Genomics Location |
13q12 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:3763
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000166 |
nucleotide binding |
GO:0000186 |
activation of MAPKK activity |
GO:0001569 |
patterning of blood vessels |
GO:0001666 |
response to hypoxia |
GO:0002040 |
sprouting angiogenesis |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
GO:0004872 |
receptor activity |
GO:0005021 |
vascular endothelial growth factor receptor activity |
GO:0005524 |
ATP binding |
GO:0005576 |
extracellular region |
GO:0005615 |
extracellular space |
GO:0005634 |
nucleus |
GO:0005730 |
nucleolus |
GO:0005737 |
cytoplasm |
GO:0005794 |
Golgi apparatus |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0006940 |
regulation of smooth muscle contraction |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
GO:0007275 |
multicellular organismal development |
GO:0007565 |
female pregnancy |
GO:0008284 |
positive regulation of cell proliferation |
GO:0019838 |
growth factor binding |
GO:0030154 |
cell differentiation |
GO:0030335 |
positive regulation of cell migration |
GO:0030522 |
intracellular receptor mediated signaling pathway |
GO:0030949 |
positive regulation of vascular endothelial growth factor receptor signaling pathway |
GO:0042802 |
identical protein binding |
GO:0048010 |
vascular endothelial growth factor receptor signaling pathway |
GO:0048661 |
positive regulation of smooth muscle cell proliferation |