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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG001651

Entrez Gene ID

2353

Official Gene Symbol

FOS

Synonyms

APN1|CNFOS

Gene name

FBJ murine osteosarcoma viral oncogene homolog

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q24.3

Known cancer genes

Yes

Protein products

V-fos FBJ murine osteosarcoma viral oncogene homolog, isoform CRA b

Proto-oncogene c-Fos

FOS protein

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatitis B

Hepatocellular carcinoma

Primary biliary cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:3796
MIM:164810
Ensembl:ENSG00000170345
HPRD:01275
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001661

conditioned taste aversion

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0003690

double-stranded DNA binding

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0005730

nucleolus

GO:0006306

DNA methylation

GO:0006351

transcription, DNA-dependent

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0006954

inflammatory response

GO:0007179

transforming growth factor beta receptor signaling pathway

GO:0007399

nervous system development

GO:0007565

female pregnancy

GO:0007568

aging

GO:0008063

Toll signaling pathway

GO:0009409

response to cold

GO:0009416

response to light stimulus

GO:0009612

response to mechanical stimulus

GO:0009629

response to gravity

GO:0009636

response to toxin

GO:0014070

response to organic cyclic compound

GO:0019717

synaptosome

GO:0030431

sleep

GO:0031668

cellular response to extracellular stimulus

GO:0032496

response to lipopolysaccharide

GO:0032570

response to progesterone stimulus

GO:0032870

cellular response to hormone stimulus

GO:0034097

response to cytokine stimulus

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0034614

cellular response to reactive oxygen species

GO:0042493

response to drug

GO:0043565

sequence-specific DNA binding

GO:0045087

innate immune response

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046983

protein dimerization activity

GO:0051090

regulation of sequence-specific DNA binding transcription factor activity

GO:0051403

stress-activated MAPK cascade

GO:0051412

response to corticosterone stimulus

GO:0051591

response to cAMP

GO:0051789

response to protein stimulus

GO:0060395

SMAD protein signal transduction

GO:0070412

R-SMAD binding

GO:0071277

cellular response to calcium ion