Gene basic information
| LiverAtlas Gene ID |
HuLG001663 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
MTOR |
|
Synonyms |
FLJ44809|FRAP|FRAP1|FRAP2|RAFT1|RAPT1 |
|
Gene name |
mechanistic target of rapamycin (serine/threonine kinase) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p36.2 |
|
Known cancer genes |
Yes |
|
Protein products |
Serine/threonine-protein kinase mTOR DJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3942
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000139 |
Golgi membrane |
|
GO:0000166 |
nucleotide binding |
|
GO:0001938 |
positive regulation of endothelial cell proliferation |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005625 |
soluble fraction |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005741 |
mitochondrial outer membrane |
|
GO:0005764 |
lysosome |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005829 |
cytosol |
|
GO:0005942 |
phosphatidylinositol 3-kinase complex |
|
GO:0005979 |
regulation of glycogen biosynthetic process |
|
GO:0006109 |
regulation of carbohydrate metabolic process |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007165 |
signal transduction |
|
GO:0007281 |
germ cell development |
|
GO:0007584 |
response to nutrient |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0010592 |
positive regulation of lamellipodium assembly |
|
GO:0012505 |
endomembrane system |
|
GO:0016020 |
membrane |
|
GO:0016049 |
cell growth |
|
GO:0016242 |
negative regulation of macroautophagy |
|
GO:0016301 |
kinase activity |
|
GO:0016310 |
phosphorylation |
|
GO:0016605 |
PML body |
|
GO:0016773 |
phosphotransferase activity, alcohol group as acceptor |
|
GO:0018105 |
peptidyl-serine phosphorylation |
|
GO:0018107 |
peptidyl-threonine phosphorylation |
|
GO:0019904 |
protein domain specific binding |
|
GO:0030163 |
protein catabolic process |
|
GO:0030425 |
dendrite |
|
GO:0030838 |
positive regulation of actin filament polymerization |
|
GO:0031295 |
T cell costimulation |
|
GO:0031529 |
ruffle organization |
|
GO:0031929 |
TOR signaling cascade |
|
GO:0031931 |
TORC1 complex |
|
GO:0031932 |
TORC2 complex |
|
GO:0031998 |
regulation of fatty acid beta-oxidation |
|
GO:0032095 |
regulation of response to food |
|
GO:0032314 |
regulation of Rac GTPase activity |
|
GO:0032868 |
response to insulin stimulus |
|
GO:0032956 |
regulation of actin cytoskeleton organization |
|
GO:0040007 |
growth |
|
GO:0043025 |
neuronal cell body |
|
GO:0043200 |
response to amino acid stimulus |
|
GO:0043610 |
regulation of carbohydrate utilization |
|
GO:0045727 |
positive regulation of translation |
|
GO:0045792 |
negative regulation of cell size |
|
GO:0045859 |
regulation of protein kinase activity |
|
GO:0046777 |
protein autophosphorylation |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0048015 |
phosphatidylinositol-mediated signaling |
|
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
|
GO:0051219 |
phosphoprotein binding |
|
GO:0051496 |
positive regulation of stress fiber assembly |
|
GO:0051534 |
negative regulation of NFAT protein import into nucleus |
|
GO:0051897 |
positive regulation of protein kinase B signaling cascade |
|
GO:0070438 |
mTOR-FKBP12-rapamycin complex |
|
GO:0071456 |
cellular response to hypoxia |
