HuLG001691

Entrez Gene ID

2538

Official Gene Symbol

G6PC

Synonyms

G6PC1|G6PT|GSD1|GSD1a|MGC163350

Gene name

glucose-6-phosphatase, catalytic subunit

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q21

Known cancer genes

Yes

Protein products

Glucose-6-phosphatase

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Glycogen storage disease

Hepatocellular carcinoma

Database cross reference

HGNC:4056
MIM:613742
Ensembl:ENSG00000131482
HPRD:01983
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0004346

glucose-6-phosphatase activity

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0005975

carbohydrate metabolic process

GO:0005977

glycogen metabolic process

GO:0005980

glycogen catabolic process

GO:0006094

gluconeogenesis

GO:0006641

triglyceride metabolic process

GO:0008202

steroid metabolic process

GO:0008645

hexose transport

GO:0010468

regulation of gene expression

GO:0015758

glucose transport

GO:0015760

glucose-6-phosphate transport

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO:0016787

hydrolase activity

GO:0030176

integral to endoplasmic reticulum membrane

GO:0035264

multicellular organism growth

GO:0042301

phosphate binding

GO:0042593

glucose homeostasis

GO:0042632

cholesterol homeostasis

GO:0046415

urate metabolic process

GO:0051156

glucose 6-phosphate metabolic process

GO:0055085

transmembrane transport