HuLG001695

Entrez Gene ID

2547

Official Gene Symbol

XRCC6

Synonyms

CTC75|CTCBF|G22P1|KU70|ML8|TLAA

Gene name

X-ray repair complementing defective repair in Chinese hamster cells 6

Gene Type

protein-coding

Chromosome

22

Genomics Location

22q13.2

Known cancer genes

Yes

Protein products

X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)

G22P1 protein

X-ray repair cross-complementing protein 6

Database cross reference

HGNC:4055
MIM:152690
Ensembl:ENSG00000196419
HPRD:01071
RefSeq Genomic nucleotide accession:AC_000065
RefSeq Genomic nucleotide gi:89161202

GO annotation

GO:0000166

nucleotide binding

GO:0000723

telomere maintenance

GO:0000783

nuclear telomere cap complex

GO:0003677

DNA binding

GO:0003690

double-stranded DNA binding

GO:0003691

double-stranded telomeric DNA binding

GO:0004003

ATP-dependent DNA helicase activity

GO:0004386

helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005624

membrane fraction

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005667

transcription factor complex

GO:0005694

chromosome

GO:0005958

DNA-dependent protein kinase-DNA ligase 4 complex

GO:0006266

DNA ligation

GO:0006281

DNA repair

GO:0006302

double-strand break repair

GO:0006303

double-strand break repair via nonhomologous end joining

GO:0008022

protein C-terminus binding

GO:0016032

viral reproduction

GO:0016787

hydrolase activity

GO:0016829

lyase activity

GO:0019047

provirus integration

GO:0019059

initiation of viral infection

GO:0043564

Ku70:Ku80 complex

GO:0045892

negative regulation of transcription, DNA-dependent

GO:0045893

positive regulation of transcription, DNA-dependent

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0051575

5'-deoxyribose-5-phosphate lyase activity

GO:0070419

nonhomologous end joining complex